That’s over 80 years of cat-chases-mouse hijinx. And while the original episodes are classics, their memes are truly iconic. Much like the thousands of SpongeBob memes and iconic quotes, it seems there’s a Tom & Jerry reaction meme for almost everything. And this meme gallery proves it! If you’re looking for some of the best, most wholesome, or just downright most entertaining memes of this cat & mouse duo, well you’ve come to the right place.

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